Somewhere between early adulthood and middle age, a compound in your cells called nicotinamide adenine dinucleotide (NAD+) begins a gradual decline. NAD+ helps power hundreds of metabolic processes and keeps a group of proteins called sirtuins active. You want them to stay active, since they can contribute to overall health and longevity.
Leonard Guarente, Ph.D., director of the Paul F. Glenn Center for Biology of Aging Research at MIT and chief scientist and cofounder of Elysium Health, discovered their role and importance. (Trailblazing research like this is one reason Elysium earned a GH Innovation Emblem.) He says sirtuins are the “guardians of health maintenance” in cells, which is why he and the Elysium Health team created a supplement their research has shown boosts NAD+ levels.
While experts are able to make some generalizations about growing older, it’s a different experience for everyone. “People are very diverse in terms of their aging rates, and the level that one person hits by age 50, another may not hit until 60,” says Morgan Levine, Ph.D., assistant professor of pathology at Yale School of Medicine.
This is why many researchers also talk about biological age, a measurement focusing on biological markers that show how your systems are actually aging. “About 68% of people will have a biological age within five years of their chronological age, but you can also find individuals who are 10 years older or younger,” she explains.
You can’t stop aging, of course, but lifestyle choices make a real difference. And research is focusing on what else can be done. “People want to play an active role in their own health maintenance,” says Dr. Guarente. He and his team at Elysium Health are looking to develop a test that will let people find out and monitor their NAD+ levels.
The hypothesis is that NAD+ levels are a better measure of aging than chronological age. And in theory, knowing them would help people make profound changes. “Successful aging is not the imitation of youth,” says Dr. Rowe. “Making yourself look better on the outside won’t impact what’s going on inside.” At the end of the day, it’s internal functions that actually matter for our health and life span.
Source: getpocket.com